The restrictions are different. Ayahuasca requires avoiding tyramine-rich foods such as aged cheeses, fermented foods, cured meats, and red wine due to MAOI activity. Eating these can cause dangerous blood pressure spikes. Iboga requires avoiding CYP2D6 inhibitors, primarily grapefruit and pomelo, which can elevate ibogaine plasma concentrations unpredictably. Both require stopping all contraindicated medications in advance, in consultation with a physician.
