Yes. Most rapé blends are based on Nicotiana rustica (mapacho), which carries a significantly higher nicotine concentration than commercial cigarette tobacco. A 2015 CDC study (Stanfill et al., PMC5704902) measured nicotine levels of 6.32 to 47.6 mg/g across 14 rapé products. Anyone with cardiovascular conditions or concerns about nicotine should consult a medical professional before using rapé or hapé.