Yes and no. Pharmacologically, they are the same medicine: Banisteriopsis caapi vine combined with a DMT-bearing admixture plant. But the word yagé (also spelled yaje or yajé) specifically belongs to the Colombian and Ecuadorian indigenous traditions: the Kamsá, Inga, Siona, and Cofán peoples of the Putumayo and Sibundoy Valley. The ceremony, the plants used, the healer’s role, and the ceremonial structure are all distinctly different from the Peruvian ayahuasca model most people encounter. Same brew, different traditions. Worth understanding the difference before you choose which path you are walking.