They are the same medicine with different names carried by different traditions. Yagé is the name used primarily in Colombia and parts of Ecuador, by the Siona, Inga, Kamsá, Cofán, and related peoples. Ayahuasca is the Quechua name used in Peru, Bolivia, and parts of Ecuador. In Brazil the same medicine is called daime in Santo Daime communities and hoasca or vegetal in the União do Vegetal. The key pharmacological difference in many Colombian and Ecuadorian preparations is the use of Diplopterys cabrerana (chagropanga) as the DMT-bearing admixture plant rather than Psychotria viridis (chacruna) used in Peru, producing different alkaloid profiles and different ceremony characters (Brito-da-Costa et al., 2020; Chambers et al., 2020).
