Plant medicine, as used on this page, refers specifically to substances held within indigenous ceremonial traditions, with protocols, healers, and cultural meaning built around them over generations. Not all psychedelics are plant medicines in this sense. Synthetic LSD, for example, is a psychedelic but not a plant medicine. Psilocybin mushrooms have indigenous ceremonial roots and are generally included in this category. The ceremonial container, the healer’s knowledge, and the integration support are considered as important to outcomes as the pharmacological compound itself.